The changes of spirometry parameter in patients with destructive pulmonary tuberculosis using collapse-forming technologies (extrapleural silicone implant plombage, valvular bronchoblocation) and lung resection

Abstract

Surgical methods can increase the effectiveness of treatment in patients with pulmonary tuberculosis. However, surgery can reduce pulmonary function, which has an adverse effect in the long-term prognosis. In this regard, the development of new methods of treatment aimed to preserve functioning lung tissue is currently relevant. The aim of the study was to compare changes in the parameters of pulmonary function after lobectomy and different collapse-forming technologies. Materials and methods. 97 patients with advanced destructive pulmonary tuberculosis were included into the study. Out of them, 28 patients underwent upper lobectomy, 25 patients — extrapleural silicone implant plombage, and 44 patients — endobronchial valve treatment of the upper lobes. All the patients performed spirometry before and after operations. Results. Pulmonary function parameters decreased by 17–19% from baseline after lobectomy; by 11–14% from baseline after extrapleural silicone implant plombage, and by 0–3% from baseline after endobronchial valve treatment. Conclusion. In patients with destructive pulmonary tuberculosis, the decrease in pulmonary function after collapsosurgical and endoscopic operations is significantly less than after lung resection.