The contribution of endo-ultrasonography rooms to the morphological verification of mediastinal lymphadenopathy

Abstract

The general prevalence of mediastinal lymphadenopathy is 0.6–0.7%. Endoultrasonography (EUS), endobronchoultrasonography (EBUS) provide very advantageous access to the mediastinum for biopsy, much less traumatic than mediastinoscopy orthoracoscopy. The advantage over percutaneous ultrasound and CT control is the lack of interposition of a large number of tissues and blood vessels.

Objective: to evaluate the contribution of the EUS and EBUS offices to the morphological verification of mediastinal lymphadenopathy. Materials and methods. EUS and EBUS offices’ reception logs, medical histories and medical records of 228 patients with mediastinal lymphadenopathy for February 2016 — February 2021.

Results. The sensitivity of EBUS with fine needle aspiration (FNA) and cytological examination of the material is 78.3%, specificity — 83.3%, accuracy — 79.3%. The sensitivity of EBUS with FNA, with histological and immunohistochemical examination of the material — 29.2%, specificity — 100%, accuracy — 43.3%. Sensitivity of EUS with FNA and cytological examination of the material — 78.3%, specificity — 100%, accuracy — 85.2%. The sensitivity of EUS with FNA, with histological and immunohistochemical examination of the material — 72.7%, specificity — 100%, accuracy — 78.6%.

Conclusion. The work of endo-ultrasonography offices has proven its effectiveness in obtaining biopsy material that allows full morphological typing of changes in the mediastinal lymph nodes. For the sake of optimization, the following may be used, cytoblocks, immunocytochemicalanalysis of biopsy material, genetic analysis of biopsy material, mastering the techniques, and the half-vest method