Keywords
Abstract
The results of examination and surgical treatment of 68 patients with various types of highly differentiated lung adenocarcinoma were analyzed. Three radiology forms of adenocarcinoma have been identified: a ground glass nodule (GGN), a solid and part-solid, which are compared with a postoperative histological material. Socalled ”сreeping”, non-invasive growth is typical of the GGN. The mucinous subtype with invasive growth prevails in solid and part-solid form of the tumor. The regional lymph node metastasis depends on the size, degree of differentiation and subtype of adenocarcinoma. There is no progression of the disease was detected in the longterm period in any case in patients who had the GGO. The five-year relapse-free period after surgical treatment with a solid and part-solid form with a mucinous subtype was 67%. The most important risk factor for disease recurrence in the postoperative period is the presence of lymphogenous metastases (N stage) upon initial detection. Adjuvant chemotherapy or targeted therapy makes it possible to increase the rates of relapse-free survival in the case of solid and part-solid forms of lung adenocarcinoma.