Abstract
Epidemics and pandemics of acute respiratory viral diseases began to recur with a certain frequency and at various scales. The largest pandemic of the last century was the spread of the “Wuhan” strain of coronavirus, which is still being analyzed to obtain scientific data and gain valuable experience. The aim of the study is to highlight the causes of unfavorable outcomes of coronavirus infection with damage to lung tissue. Material and methods. The medical histories of 295 patients with “Covid pneumonia” who were hospitalized were studied. All general clinical (laboratory, radiological and instrumental) tests were carried out. Two study groups were formed: 1st group — survivors (control group), 2nd group — deceased (study group). Results. In the group of deceased patients, statistically significant criteria with high odds were a positive PCR test for SARS-CoV-2 (80.77%) (OR 7.42, CI [3.873; 15.033]), concomitant pathology — 96.2% (р<0.05), among which type 2 diabetes mellitus (37.2%, р<0.05), obesity (70.5%, р<0.05), coronary heart disease (57.7%, р<0,05), chronic kidney (42.3%, р<0,05) and gastrointestinal tract (67.9%, р<0.05) diseases, IQR 3. Respiratory failure grade 3 increased the risk of death by 15.43 (CI [5.3585; 54.7184]) (р<0.05). Conclusion. According to the results of the analysis of data in patients admitted for inpatient treatment, the most significant diseases affecting the further outcome were diseases of a metabolic nature and of cardiovascular system. The use of identified predictors of death makes it possible to adjust the indications for hospitalization during a pandemic.