The use of antibacterial drugs for the treatment of inflammatory periodontal diseases (review)

Abstract

The high prevalence of inflammatory periodontal diseases worldwide is a pressing issue in dentistry. One of the etiologic factors in the development of periodontitis is periodontopathogenic bacteria, which provoke the development of inflammation accompanied by destructive processes in the bone and connective tissue of the periodontium. The main goal of periodontal treatment is to restore the microbiological balance of periodontal tissues, eliminate periodontopathogens, prevent disease progression and restore the level of clinical attachment. The systematic review presents the results of modern studies on the use of drugs based on chlorhexidine, metronidazole and tetracycline antibiotics for the treatment of periodontitis. In view of the short-term effect of the active substance on periodontopathogenic microflora, it is necessary for domestic manufacturers to develop drugs with antibacterial activity that have a prolonged effect in periodontal tissues for the effective treatment of periodontitis.