Regenerative rehabilitation in injuries of cartilaginous tissue (review)

Abstract

The review article is devoted to the analysis of the current state of regenerative and rehabilitative treatments in orthopedics, the possibilities of restoring the functioning of cartilaginous tissue lost due to aging, injuries or di seases. An overview of the main methods and approaches to enable effective regenerative and rehabilitation measures is given. The study of the molecular genetic basis of mechanotransduction and mechanotherapy will allow to identify genes and molecules, the
expression levels of which can serve as biomarkers of the effectiveness of regenerative-rehabilitation measures. These mechanisms are potential therapeutic targets for stimulating cartilage regeneration. The focus of the article is on the choice of an individual approach, both when conducting basic scien tific research and developing rehabilitation programs. All this will significantly improve patient outcomes.