Abstract
Diabetes mellitus (DM), which is often followed by pul- monary tuberculosis, is an area under multi-organ fail- ure - dysfunction of multiple organs and systems. TB drugs (TAP), having Organotropona, have an additional damaging effect on the organs - liver, kidney, central and peripheral nervous, cardiovascular system in these patients. Patients with comorbidity, in addition to causal and hypoglycemic therapy, need, as a rule, the appoint- ment of several groups of drugs escort that leads to forced polypharmacy, adverse reactions to anti-TB drugs development, pathogenesis, and often hypoglycemic, which leads to a decrease in adherence of co-pathology TB patients to the treatment.