Abstract
Indications and algorithm of M. tuberculosis, genotyping methods (spoligotyping, different MIRU-VNTR typing, IS6110-RFLP) use ae discussed. Results' interpretation and jpportunities of the methods in epidemiologic monitoring of M. tuberculosis population, operational epidemiological analysis and TB surveillance prognosis in high drug-resistant disease causing strains of epidemiologically and clinically significant genotypes are demonstrated.