Abstract
Introduction. Despite there are studies demonstrating a correlation between Helicobacter pylori infection of the gastrointestinal tract and lesions of the oral mucosa, there is currently no systematization of clinical manifestations. The purpose of the study. To systematize scientific data on possible clinical manifestations of Helicobacter pylori infection in the oral cavity. Materials and methods. In order to achieve this goal, a comprehensive analysis of modern scientific publications of domestic and foreign researchers for the period from 2015 to 2025, posted on the electronic platforms eLIBRARY and PubMed, was carried out. 184 sources on the topic were analyzed, of which 36 publications corresponding to modern views and concepts were selected to provide summarized data. Results. Based on the conducted studies, a pathogenetic correlation was found between gastrointestinal diseases caused by Helicobacter pylori and the development of various oral diseases, including damage to the integrity of hard dental tissues, progression of inflammatory processes in periodontal tissues, changes in the qualitative and quantitative composition of mixed saliva, and lesions of the mucous membrane. Conclusion. Thus, the spectrum of Helicobacter pylori effects on the body is multifaceted and is directly reflected in the form of subjective and objective manifestations in the oral cavity, being the initial segment of the digestive tract, while the lack of timely treatment affects not only the quality of life, but can also lead to unfavourable outcomes. Timely diagnosis of the presence of Helicobacter pylori infection in the oral cavity allows for high-quality differential diagnosis from other conditions with similar manifestations, in particular with a symptom complex of dentures’ structural materials intolerance, and in case of combined pathologies, to minimize clinical manifestations by choosing a rational treatment strategy.